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Hearing Loss

Certain cases of hearing loss have been associated with autoimmunity. Such cases may involve an immune response targeting the inner ear alone or the hearing loss may be one symptom of systemic autoimmune disorders such as Cogan's syndrome, Wegener’s granulomatosis, polyarteritis nodosa, and systemic lupus erythomatosis. Cases in which hearing loss is the only symptom are termed primary autoimmune inner ear disease (AIED). When hearing loss occurs in the context of systemic autoimmunity this is known as secondary AIED. Because of the difficulty of diagnosing patients primary AIED, certain diagnostic markers have been identified to support diagnosis. These include the 68kD (hsp-70) antibodies and P0 antibodies. If treated promptly, patients with detectable levels of these antibodies have been shown to respond to immunosuppressive treatments with cessation of hearing loss or recovery of hearing.

Products Available

Code Product Description Determinations Product Insert
*1190 OTOblot™ 68kD (hsp-70) Antibody Western Blot Assay
 20
*1192 P0 Antibody Western Blot Assay 20 N/A

*Available only outside of US
North America: 800.537.8378 | International: 716.691.0091 | Fax 716.691.0466
60 Pineview Drive | Buffalo, NY 14228 USA